human hepatoma cell line heparg (Biopredic)
90
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Biopredic
human hepatoma cell line heparg
Human Hepatoma Cell Line Heparg, supplied by Biopredic, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/heparg+human+hepatoma+cell+line/human+hepatoma+cell+line+heparg/pmc11125674-28-5-17
Average 90 stars, based on 1 article reviews
Human Hepatoma Cell Line Heparg, supplied by Biopredic, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/heparg+human+hepatoma+cell+line/human+hepatoma+cell+line+heparg/pmc11125674-28-5-17
Average 90 stars, based on 1 article reviews
human hepatoma cell line heparg - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Influence of lyophilization primary drying time and temperature on porous silk scaffold fabrication for biomedical applications. Article Snippet: Funding information Worcester Polytechnic Institute Abstract Lyophilization of protein solutions, such as silk fibroin (silk), produces porous scaffolds useful for tissue engineering (TE).. The impact of modifying lyophilization primary drying parameters on scaffold properties has not yet been explored previously.. In this work, changes to primary drying duration and temperature were investigated using 3%, 6%, 9%, and 12% (w/v) silk solutions, via protocols labeled as Long Hold, Slow Ramp, and Standard. Article Title: HepaRG Maturation in Silk Fibroin Scaffolds: Toward Developing a 3D In Vitro Liver Model. Article Snippet: In vitro liver models are necessary tools for the development of new therapeutics.. HepaRG cells are a commonly used cell line to produce hepatic progenitor cells and hepatocytes.. This study demonstrates for the first time the suitability of 3% silk scaffolds to support HepaRG growth and differentiation. Article Title: Development of an in vitro model to screen CYP1B1-targeted anticancer prodrugs Article Snippet: HepaRG TM (human hepatoma cell line) cells and additives for HepaRG Growth and Differentiation mediums were purchased from Cell Culture:Article Title: Performance of HepaRG and HepG2 cells in the high-throughput micronucleus assay for in vitro genotoxicity assessment. Article Snippet: The micronucleus (MN) assay is a core test used to evaluate genotoxic potential of xenobiotics.. The traditional in vitro MN assay is usually conducted in cells lacking metabolic competency or by supplementing cultures with an exogenous rat S9 metabolic system, which creates a significant assay limitation for detecting genotoxic metabolites.. Our previous study demonstrated that compared to HepG2, HepaRG cells exhibited a significantly higher level of CYP450 enzyme activities and detected a greater portion of genotoxic carcinogens requiring metabolic activation using the Comet assay. Article Title: Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays. Article Snippet: Propranolol is a widely used β-blocker that can generate a nitrosated derivative, N-nitroso propranolol (NNP).. NNP has been reported to be negative in the bacterial reverse mutation test (the Ames test) but genotoxic in other in vitro assays.. In the current study, we systematically examined the in vitro mutagenicity and genotoxicity of NNP using several modifications of the Ames test known to affect the mutagenicity of nitrosamines, as well as a battery of genotoxicity tests using human cells. Article Title: Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay. Article Snippet: In vitro genotoxicity testing that employs metabolically active human cells may be better suited for evaluating human in vivo genotoxicity than current bacterial or non-metabolically active mammalian cell systems.. In the current study, 28 compounds, known to have different genotoxicity and carcinogenicity modes of action (MoAs), were evaluated over a wide range of concentrations for the ability to induce DNA damage in human HepG2 and HepaRG cells.. DNA damage dose–responses in both cell lines were quantified using a combination of high-throughput high-content (HTHC) CometChip technology and benchmark dose (BMD) quantitative approaches. |